Milk can form a film on the surface of gastric mucosa, which affect the absorption of drug as well as drug efficacy. At the same time, milk might have undesirable chemical or physical reactions with some drugs. The calcium, phosphorus, and iron in milk easily react with organic substances in medicine and form insoluble compounds,some might be harmful to human body. Below are 5 types of medicine that should not take with milk.
Antibiotics
Metal ions in milk can combine with quinolones antibiotics(such as Ciprofloxacin Tablets), tetracyclines antibiotics(such as Tetracycline HCl Capsules), oxytetracycline, erythromycin, metronidazole and other antibiotics to form insoluble chelates that affect absorption and reduce antibacterial effects.
Calcium or aluminum preparation
The protein in milk can form a gel with calcium lactate, calcium gluconate, aluminum hydroxide and other calcium and aluminum preparations, which affects absorption and increases gastrointestinal burden.
Iron preparations
Iron deficiency anemia is a common disease in women and children. Calcium ions in milk can compete with iron in the duodenal absorption site and affect the efficacy. So do not drink milk while taking iron-containing drugs (such as Ferrous Sulfate + Folic Acid Tablets).
Antacids
Taking antacids such as bismuth potassium citrat and sodium bicarbonate will react with milk, and cause milk-alkali syndrome.
Antidepressants
Do not drink milk while taking monoamine oxidase inhibitors antidepressants (such as Paroxetine HCl Anhydrous, Safinamide). Milk is rich in tyramine, and when monoamine oxidase is inhibitted, tyramine will accumulate in large quantities, causing a surge in blood pressure and arrhythmia.
It is best to take the medicine with water, not with milk or tea or other kind of drink. For baby that should have breast milk , there should be intervals after taking the medicine.
